The Link between Salivary Surfactant-Protein D and Dementia in Nursing Home Dementia Patients

Authors

  • Celine Budding University College Roosevelt
  • Toon Holman University College Roosevelt

DOI:

https://doi.org/10.25609/sure.v3.2535

Keywords:

Dementia, surfactant protein D, innate immunity, saliva,

Abstract

Recently, serumal surfactant protein D (SP-D) has been shown to correlate with the development of dementia.
As SP-D can be measured reliably in saliva, this might provide opportunities for a non-invasive biomarker. This
preliminary study aims to determine a possible difference between the levels of salivary SP-D in nondemented
elderly and late stage demented elderly. Results indicate a significant difference between demented subjects and controls, and between male and female demented subjects. This suggests SP-D could be used as a biomarker to improve detection of dementia. Further research should focus on early-stage dementia and the role of innate immunity in dementia.

Additional Files

Published

2017-12-05

Issue

Vol. 3 (2017): Student Research Conference 2017

Section

Natural and Biomedical Sciences

License

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